Organ of Corti culture for functional analysis of precursor, support and hair cells

Em mamíferos a perda das células ciliadas determina perda auditiva neurosensorial permanente, já que estas células encontram-se em diferenciação terminal e seus precursores não mais entram no ciclo celular...

Loss of hair cells in mammals causes permanent sensorineural hearing loss, as these cells are terminally-differentiated and their precursors do not reenter the cell cycle. The aims of this study were to establish primary cell cultures and subcultures of organ of Corti...